There are many ways. If you just want to grab a copy, use substr():
$first_byte = substr($a, 0, 1);If you want to modify part of a string, the simplest way is often to use substr() as an lvalue:
substr($a, 0, 3) = "Tom";Although those with a pattern matching kind of thought process will likely prefer
$a =~ s/^.../Tom/;